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dc.contributor.authorWhalley, Gillian
dc.date.accessioned2015-09-09T02:27:41Z
dc.date.available2015-09-09T02:27:41Z
dc.date.issued2014-11-18
dc.identifier.issn2047-2404
dc.identifier.urihttps://hdl.handle.net/10652/3016
dc.description.abstractAim To develop age-, sex-, and ethnic-appropriate normative reference ranges for standard echocardiographic measurements of the left heart by combining echocardiographic measurements obtained from adult volunteers without clinical cardiovascular disease or significant cardiovascular risk factors, from multiple studies around the world. Methods and results The Echocardiographic Normal Ranges Meta-Analysis of the Left heart (EchoNoRMAL) collaboration was established and population-based data sets of echocardiographic measurements combined to perform an individual person data meta-analysis. Data from 43 studies were received, representing 51 222 subjects, of which 22 404 adults aged 18–80 years were without clinical cardiovascular or renal disease, hypertension or diabetes. Quantile regression or an appropriate parametric regression method will be used to derive reference values at the 5th and 95th centile of each measurement against age. Conclusion This unique data set represents a large, multi-ethnic cohort of subjects resident in a wide range of countries. The resultant reference ranges will have wide applicability for normative data based on age, sex, and ethnicity.en_NZ
dc.language.isoenen_NZ
dc.publisherOxford University Press on behalf of the European Society of Cardiologyen_NZ
dc.relation.urihttp://ehjcimaging.oxfordjournals.org/content/15/3/341en_NZ
dc.rights. All rights reserved. © The Author 2013.en_NZ
dc.subjectechocardiographyen_NZ
dc.subjectreference rangesen_NZ
dc.subjectmeta-analysisen_NZ
dc.titleA meta-analysis of echocardiographic measurements of the left heart for the development of normative reference ranges in a large international cohort: the EchoNoRMAL studyen_NZ
dc.typeJournal Articleen_NZ
dc.rights.holderOxford University Pressen_NZ
dc.identifier.doihttp://dx.doi.org/10.1093/ehjci/jet240en_NZ
dc.subject.marsden110201 Cardiology (incl. Cardiovascular Diseases)en_NZ
dc.identifier.bibliographicCitationThe Echocardiographic Normal Ranges Meta-Analysis of the Left heart EchoNoRMAL)Collaboration. (2013). A meta-analysis of echocardiographic measurements of the left heart for the development of normative reference ranges in a large international cohort: the EchoNoRMAL study. European Heart Journal – Cardiovascular Imaging (2014) 15, 341–348. doi:10.1093/ehjci/jet240 NOTE: Available from link below.en_NZ
unitec.institutionUnitec Institute of Technologyen_NZ
unitec.publication.spage341en_NZ
unitec.publication.lpage348en_NZ
unitec.publication.volume15en_NZ
unitec.publication.titleEuropean Heart Journal – Cardiovascular Imagingen_NZ
unitec.peerreviewedyesen_NZ
dc.contributor.affiliationUnitec Institute of Technologyen_NZ
unitec.identifier.roms56939
unitec.institution.studyareaHealth Sciences


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