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dc.contributor.authorWang, Jing
dc.contributor.authorMcLenachan, P.A.
dc.contributor.authorBiggs, Patrick J.
dc.contributor.authorWinder, Linton
dc.contributor.authorSchoenfeld, Barbara I.K.
dc.contributor.authorNarayan, Vinay V.
dc.contributor.authorPhiri, Bernard J.
dc.contributor.authorLockhart, Peter
dc.date.accessioned2015-03-16T21:20:46Z
dc.date.available2015-03-16T21:20:46Z
dc.date.issued2013-05-15
dc.identifier.issn1467-5463
dc.identifier.issn1477-4054
dc.identifier.urihttps://hdl.handle.net/10652/2644
dc.description.abstractThere is much interest in using high-throughput DNA sequencing methodology to monitor microorganisms, complex plant and animal communities. However, there are experimental and analytical issues to consider before applying a sequencing technology, which was originally developed for genome projects, to ecological projects. Many of these issues have been highlighted by recent microbial studies. Understanding how high-throughput sequencing is best implemented is important for the interpretation of recent results and the success of future applications. Addressing complex biological questions with metagenomics requires the interaction of researchers who bring different skill sets to problem solving. Educators can help by nurturing a collaborative interdisciplinary approach to genome science, which is essential for effective problem solving. Educators are in a position to help students, teachers, the public and policy makers interpret the new knowledge that metagenomics brings. To do this, they need to understand, not only the excitement of the science but also the pitfalls and shortcomings of methodology and research designs. We review these issues and some of the research directions that are helping to move the field forward.en_NZ
dc.language.isoenen_NZ
dc.publisherOxford University Pressen_NZ
dc.rights© The Author 2013. Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.comen_NZ
dc.subjectmetagenomicsen_NZ
dc.subjectenvironmental bio-monitoringen_NZ
dc.subjecthigh-throughput sequencingen_NZ
dc.titleEnvironmental bio-monitoring with high-throughput sequencingen_NZ
dc.typeJournal Articleen_NZ
dc.rights.holderThe Authorsen_NZ
dc.identifier.doidoi: 10.1093/bib/bbt032en_NZ
dc.subject.marsden0602 Ecologyen_NZ
dc.subject.marsden060407 Genome Structure and Regulationen_NZ
dc.identifier.bibliographicCitationWang, J., McLenachan, P.J., Biggs, P.J., Winder, L. H., Schoenfeld, B.I.K., Narayan, V.V., Phiri, B.J., and Lockhart, P.J. (2013). Environmental bio-monitoring with high-throughput sequencing. Briefings in Bioinformatics.en_NZ
unitec.institutionInstitute of Environmental Science and Research (Upper Hutt)en_NZ
unitec.institutionMassey University Genome Serviceen_NZ
unitec.institutionUnitec Institute of Technologyen_NZ
unitec.institutionUniversity of the South Pacificen_NZ
unitec.publication.spage1en_NZ
unitec.publication.lpage14en_NZ
unitec.publication.titleBriefings in Bioinformaticsen_NZ
unitec.peerreviewedyesen_NZ
unitec.identifier.roms55058en_NZ
unitec.institution.studyareaNatural Sciences


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