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    Association between endothelin type A receptor haplotypes and mortality in coronary heart disease

    Whalley, Gillian

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    Peronalized Medicine.pdf (1.105Mb)
    Date
    2012
    Citation:
    Ellis, K. L., Pilbrow, A. P., Potter, H. C., Frampton, C. M., Doughty, R. N., Whalley, G. A., ... & A Cameron, V. (2012). Association between endothelin type A receptor haplotypes and mortality in coronary heart disease. Personalized Medicine, 9(3), 341-349.
    Permanent link to Research Bank record:
    https://hdl.handle.net/10652/2116
    Abstract
    Coronary heart disease (CHD) encompasses a range of conditions including unstable angina, acute myocardial infarction (MI) and sudden ischemic death, characterized by the common pathophysiologic process of atherosclerotic plaque rupture and thrombosis [1,2] . CHD patients with a high risk of poor clinical outcome are identified with the use of biochemical and clinical measurements, including circulating cardiac markers and echocardiographic indices. Prognosis of patients varies widely and genetic factors are likely to play an important role in the pathogenesis and progression of disease. The identification of genes that influence progression of disease may inform future patient management and care.
    Keywords:
    coronary heart disease, endothelin-type A receptor, genetics, haplotype, mortality
    ANZSRC Field of Research:
    110201 Cardiology (incl. Cardiovascular Diseases)
    Copyright Holder:
    Future Science Group

    Copyright Notice:
    All rights reserved
    Rights:
    This digital work is protected by copyright. It may be consulted by you, provided you comply with the provisions of the Act and the following conditions of use. These documents or images may be used for research or private study purposes. Whether they can be used for any other purpose depends upon the Copyright Notice above. You will recognise the author's and publishers rights and give due acknowledgement where appropriate.
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